肖春
食用菌研究发展中心 副研究员 |
研究领域: 食药用菌多糖降血糖功能机制研究。 |
代表论著: 1. Chun Xiao#, Chunwei Jiao#, Yizhen Xie, Linhui Ye, Qianqing Li, Qingping Wu*. Grifola frondosa GF5000 improves insulin resistance by modulation the composition of gut microbiota in diabetic rats. J Funct Foods, 2021, 77:104313. 2. Chun Xiao#, Qingping Wu#*, Yizhen Xie, Jianbin Tan, Yinrun Ding, LijuanBai. Hypoglycemic mechanisms of Ganoderma lucidum polysaccharides F31 in db/db mice via RNA-seq and iTRAQ. Food Funct, 2018, 9: 6496-6508. 3. Chun Xiao#, Qingping Wu#*, Jumei Zhang, Yizhen Xie, Jianbin Tan. Antidiabetic activity of Ganoderma lucidum polysaccharides F31 down-regulated hepatic glucose regulatory enzymes in diabetic mice. J Ethnopharmacol, 2017, 196: 47-57. 4. Chun Xiao#, Qingping Wu#*, Yizhen Xie, Jumei Zhang, Jianbin Tan. Hypoglycemic effects of Grifola frondosa (Maitake) polysaccharides F2 and F3 through improvement of insulin resistance in diabetic rats. Food Funct, 2015, 6: 3567-3575. 5. Chun Xiao#, Qingping Wu#*, Wen Cai, Jianbin Tan, Xiaobing Yang, Jumei Zhang. Hypoglycemic effect of Ganoderma lucidum polysaccharides in type 2 diabetic mice. Arch Pharm Res, 2012, 35:1793-1801. 6. Chun Xiao, Qingping Wu*, Jianbin Tan, Wen Cai, Xiaobing Yang, Jumei Zhang. Inhibitory effects on alpha-glucosidase and hypoglycemic effects of the crude polysaccharides isolated from 11 edible fungi. J Med Plants Res, 2011, 5: 6963-6967. 7. 肖春, 吴清平*, 蔡玟, 谭剑斌, 黄俊明, 杨小兵. 灵芝粗多糖对糖尿病小鼠的降血糖作用. 中国食用菌,2011,03:37-39. 8. Yinrun Ding, Chun Xiao, Qingping Wu*, Yizhen Xie. The mechanisms underlying the hypolipidaemic effects of Grifola frondosa in the liver of rats, Front Microbiol, 2016:1186. 9.吴清平*, 肖春, 杨小兵, 张菊梅. 食(药)用菌多糖类物质降血糖作用及其机理研究进展. 食用菌学报,2009, 16:80-86. |
主持项目(省部级以上): 1.广东省自然科学基金项目,面上项目,灵芝多糖F31调节GK表达改善肝脏糖代谢紊乱的分子机制研究,2021-01 至 2023-12,已立项; 2.广东省自然科学基金,博士启动,灵芝活性多糖F31的一级结构解析及其调控肝脏糖异生信号转导的研究(2015A030310001),2015-08 至 2018-08,10万元,已结题; 3.广东省省级产业技术研究与开发计划项目,食药用菌降血糖功能新产品的研制及产业化示范,2012-08 至 2015-07,100万,已结题。 |
授权专利: 1.吴清平, 肖春, 谢意珍, 杨小兵, 李森柱. Process for Preparation of a Grifola frondosa Polysaccharides F2 and Its Hypoglycemic Activity, 2018-12-18,美国,US10155822B2. 2.吴清平, 肖春, 杨小兵, 谢意珍, 李森柱. 灰树花多糖F2的制备方法及其降血糖功能,2016-08-17, 中国,ZL201310733480.8. 3.吴清平, 肖春, 杨小兵, 谢意珍, 李森柱. 灵芝多糖F31的制备方法及其降血糖功能,2013-11-13,中国,ZL201210056087.5. |
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